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Histiocytic Sarcoma in Dogs

Jul 26, 2018

Localized histiocytic sarcoma,  disseminated histiocytic sarcoma and malignant histiocytosis are fairly rare tumors overall but occur with high incidence in Bernese Mountain dogs, Rottweilers, Flat Coated Retrievers, and Golden Retrievers. Histiocytic sarcomas are very aggressive tumors, and can therefore become very invasive (destroy normal surrounding tissues) as well as have a high rate of metastasis (spreading to other areas of the body). Localized histiocytic sarcoma lesions most commonly are found in the spleen, lymph nodes, lung, bone marrow, skin, brain, and joints of the limbs. Disseminated histiocytic sarcoma and malignant histiocytosis are multi-system, rapidly progressive diseases in which there is simultaneous involvement of multiple organs such as the spleen, lymph nodes, lung, bone marrow, and skin.